Identifikasi Senyawa Metabolit Sekunder dan Analisis Senyawa Berpotensi Obat Hasil Ekstrak Kombinasi Daun Sirih Hijau (piper betle L) dan Daun Sirsak (Annona muricata L)

MBERE, Marina Anriani (2025) Identifikasi Senyawa Metabolit Sekunder dan Analisis Senyawa Berpotensi Obat Hasil Ekstrak Kombinasi Daun Sirih Hijau (piper betle L) dan Daun Sirsak (Annona muricata L). Undergraduate thesis, Universitas Katolik Widya Mandira Kupang.

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Abstract

One of the traditional medicines widely used in Indonesian society is green betel leaves (Piper betle L) and soursop leaves (Annona muricata). Soursop leaves are widely used by the community to treat various diseases such as cancer, stabilize blood sugar levels, and lung disease. Meanwhile, green betel leaves are widely used as antioxidants and cough remedies. This study aims to determine the physicochemical properties, phytochemical screening, identification of chemical compounds from GC-MS analysis, and analysis of potential medicinal compounds from the combination extract of green betel leaves and soursop leaves. Physicochemical analysis includes density test, solubility test, and boiling point test. Phytochemical screening includes identification of alkaloids, flavonoids, tannins, saponins, triterpenoids, and steroids. Chemical component analysis includes TLC and GC-MS analysis. Potential medicinal compounds from the combination extract of green betel leaves and soursop leaves were identified from the GC-MS analysis results. The research method used was Laboratory Experiment. The results of the physicochemical analysis showed that the combination extract of green betel leaves and soursop leaves had a density of 0.78 g/mL, was soluble in aquades, ethanol, chloroform, and acetone, and had a boiling point of 82°C. The results of the phytochemical screening showed that the combination extract of green betel leaves and soursop leaves contained alkaloid, flavonoid, tannin, saponin, and steroid compounds. The results of the GC-MS analysis showed that the combination extract of green betel leaves and soursop leaves contained compounds such as hexadecane, heptadec-8-ene, nonadecane, 2- tridecanol, oxirane-tetradecyl, 9-hexadecanoic acid, methyl ester, hexadecanoic acid, methyl ester, hexadecanoic acid, 7-hexadecanoic acid, methyl ester, methyl gamma-linolenate, 9,12-octadecadienoic acid-methyl ester, 2-hexadecen-1- ol,3,7,11,15-tetramethyl, 1,2-benzenedicarboxylic acid, 9-eicosene, 1H-purin-6- amine, 17-pentatriacontene, silicon oil, neophytadiene, dodecanoic acid,1,2,3- propanetriyl ester, hexadecenoic acid,2-hydroxy-1,3-propanediyl ester. The results of the GC-MS analysis showed that the potential medicinal compounds from the combination extract of green betel leaves and soursop leaves were hexadecenoic acid, phytol, and hexadecenoic acid methyl ester.

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