Senyawa-Senyawa Aktif Anti kanker Dari Tumbuh-Tumbuhan Obat Yang Digunakan Oleh Masyarakat Di Kabupaten Belu Dalam Pengobatan Penyakit Kanker Secara Tradisional

LELO, Eduardo Laurentius (2021) Senyawa-Senyawa Aktif Anti kanker Dari Tumbuh-Tumbuhan Obat Yang Digunakan Oleh Masyarakat Di Kabupaten Belu Dalam Pengobatan Penyakit Kanker Secara Tradisional. Undergraduate thesis, Universitas Katolik Widya Mandira Kupang.

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Abstract

This study aims to determine the plants used by the people of Derok Faturene Village, Belu Regency as anticancer, the active compounds contained in these plants and how their cytotoxic activity is. The method used is interviews and literature study. The results of this study, found 22 plants that have cytotoxic activity as anticancer. These plants are; Bidens pilosa L, Indigofera tinctoria, Moringa oliefera, Sterculia foetida, Euphorbia thymifolia L, Euphorbia hirta, Verbena urticifolia L, Euphorbia prostrata Ariton, Tilia Americana L, Onanis spinosa L, Salix alba L, Quercus castaneifolia CAMey , Eleusine indica (L, Proboscidea, Smilchiaparchiax minor) gaertn.DC, Wendlandia burkilli, Phyllanthus urinaria, and Phyllanthus nurarii. Characterization of active compounds, namely quercetin (from the flavonoid group), nor-securinine (from the alkaloid group), lignans (from the phenylpropanoid group), beta-sitosterol (from the steroid group), cleistanthol (from the diterpenoid group), and sarsaparilloside (from the saponin group). These active compounds can attack cancer cells such as; HeLa, HepG2, KB 3-1, HCT116, MCF-7 cells, MDA-MB- 231, HCT-8, p65, T24, HT-29, HEK, 293, HEK 293, A549 cells, and LL.

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